This site needs JavaScript to work properly. Many of the previously effective therapeutic agents are no longer viable. Microbes Infect. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. With over 600,000 new infections reported each year, Neisseria gonorrhoeae (N. gonorrhoeae) has become the second most common, sexually transmitted infection in the United States. Genital Chlamydia trachomatis and Neisseria gonorrhoeae infections among women in sub-Saharan Africa: A structured review. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. This site needs JavaScript to work properly. Within the developing countries, gonorrhea caused by resistant strains of N. gonorrhoeae has become hyperendemic. 1997 Sep;65(9):3736-42. doi: 10.1128/IAI.65.9.3736-3742.1997. Antimicr …  |  Methods: Disseminated gonococcal infection occurs in 0.5 to 3% of patients with gonorrhea (Chapter 307). Methods: Isolates from 16 242 gonorrhoea episodes at sexual health clinics within the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) underwent antimicrobial susceptibility testing. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Sep. Report No. 2019 May 22;9(5):e025808. Antibiotic sensitivity patterns of penicillinase-positive and penicillinase-negative strains of Neisseria gonorrhoeae isolated in … Because N. gonorrhoeae infections are not reportable in Germany, only limited data on disease epidemiology and antimicrobial susceptibility patterns are available. The mean prevalence was higher for populations with tubal factor infertility (3.6%, 95% CI 0.9%-7.7%) and mixed cause and unexplained infertility (3.6%, 95% CI 0.0% to 11.6%) compared with other diagnoses, such as ovarian and non-tubal infertility (0.1%, 95% CI 0.0% to 0.8%), and for secondary (2.5%, 95% CI 0.2% to 6.5%) compared with primary (0.5%, 95% CI 0.0% to 1.7%) infertility. Epub 2011 Sep 28. Gonorrhoea in men: clinical and diagnostic aspects. Background: The epidemiology of sexually transmitted infections (STIs) and the role of commercial heterosexual sex networks in driving STI transmission in the Middle East and North Africa (MENA) region remain largely unknown. Dubbink JH, Verweij SP, Struthers HE, Ouburg S, McIntyre JA, Morré SA, Peters RP. No studies to date have examined the genomic epidemiology of gonorrhoea in the Western Pacific Region, where the incidence of gonorrhoea is particularly high. van Oostrum N, De Sutter P, Meys J, Verstraelen H. Hum Reprod. Among Neisseria species, strains of N. lactamica are unique in their ability to use lactose; this characteristic may enhance populations of N. lactamica in the throats of younger children. Objectives: To describe trends in prevalence, susceptibility profile and risk factors for MDR Neisseria gonorrhoeae (MDR-NG) in England and Wales. 1986 Feb;153(2):340-5. doi: 10.1093/infdis/153.2.340.  |  The rapid increase in reported disease in many developed countries noted in the 1960s and 1970s has been followed by stable or declining disease rates. Get the latest research from NIH: https://www.nih.gov/coronavirus. Neisseria gonorrhoeae, also known as gonococcus (singular), or gonococci (plural) is a species of Gram-negative diplococci bacteria isolated by Albert Neisser in 1879. 6 Approach to the revision of STI guidelines 8 References 9 WHO guidelines for the treatment of Neisseria gonorrhoeae 10 1. STI epidemiology and burden 6 Why new guidelines for the prevention, treatment and management of STIs? 2013 Jul;28(7):1809-15. doi: 10.1093/humrep/det096. Infection with Neisseria gonorrhoeae is a global problem. J Infect Dis. Gonorrhea, which may become untreatable due to multiple resistance to available antibiotics, remains a public health problem worldwide. Once considered a public nuisance of the developed countries, gonorrhea is now established as a leading worldwide public health problem. Epub 2009 Nov 1. We investigated the epidemiology of the mutant gyrase A gene, a reliable predictor of ciprofloxacin resistance, in Neisseria gonorrhoeae infections at UCLA Health in Los An-geles, California, USA, during November 1, 2015–August 31, 2016. Get the latest public health information from CDC: https://www.coronavirus.gov. Infected men may experience pain or burning with urination, discharge from the penis, or testicular pain. Agency for Healthcare Research and Quality (US). Future studies using these methods will provide valuable knowledge of the ecology and epidemiology of gonorrhea. Epidemiology and treatment of penicillinase-producing Neisseria gonorrhoeae. Neisseria gonorrhoeae, the gonococcus, is a non-spore-forming, nonmotile bacterium that appears under the microscope as a Gram-negative coccus occurring in pairs (diplococci) with flattening of the adjacent sides. Sex Transm Infect. If left untreated, complications may include pelvic inflammatory disease and infertility. Int J STD AIDS. We investigated the epidemiology of the mutant gyrase A gene, a reliable predictor of ciprofloxacin resistance, in Neisseria gonorrhoeae infections at UCLA Health in Los Angeles, California, USA, during November 1, 2015–August 31, 2016. Background. Epidemiology.  |  Global epidemiology of Neisseria gonorrhoeae in infertile populations: systematic review, meta-analysis and metaregression Sex Transm Infect . Symptomatic gonorrhea results in urethritis in males and cervicitis in females. Neisseria gonorrhoeae causes more than 100 million infections worldwide each year, 1 with an estimated 820 000 in the USA. Prospero registration number: Background.  |  Neisseria gonorrhoeae (Chapter 307) is a common cause of polyarthralgias and arthritis as well as oligoarticular arthritis and tenosynovitis in young, healthy patients. Epidemic spread of plasmid-mediated tetracycline resistant Neisseria gonorrhoeae in Zaire. Gonorrhoea prevalence in infertile populations is several folds higher than that in the general population, with even higher prevalence in women with tubal factor infertility and in individuals with secondary infertility. Current Centers for Disease Control and Prevention guidelines recommend that clinicians empirically treat the sex partners of persons with Neisseria gonorrhoeae (GC) or Chlamydia trachomatis (CT) infection before confirming that they are infected. Risk of bias was assessed using four quality domains. No commercial re-use. Neisseria gonorrhoeae, also known as gonococcus (GC), is a gram-negative diplococcus which is one of the most common sexually transmitted microorganisms, and causes gonorrhea. Background: Antimicrobial-resistant Neisseria gonorrhoeae is a major threat to public health. Chemaitelly H, Harfouche M, Blondeel K, Matsaseng TC, Kiarie J, Toskin I, Abu-Raddad LJ. Yoshida S, Urabe S, Mizuguchi Y. Infect Immun. Clipboard, Search History, and several other advanced features are temporarily unavailable. Introduction . Within the developing countries, gonorrhea caused by resistant strains of N. gonorrhoeae has become hyperendemic. A systematic literature review was conducted up to 29 April 2019 on international databases and WHO regional databases, and reported following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The process usually settles in one or two joints and … Infection may involve the genitals, mouth, and/or rectum. 1997 Jun;73(3):194-7. doi: 10.1136/sti.73.3.194. Unlike N. gonorrhoeae and N. meningitidis, N. lactamica has not been implicated as a primary pathogen, although it may be an opportunistic pathogen. Competing interests: The authors have no conflicts of interests to declare. 1979 Apr-Jun; 6 (2 Suppl):152–158. 1985 Feb;102(2):229-43. doi: 10.7326/0003-4819-102-2-229. … Pooled mean prevalence by relevant strata was estimated using random-effects meta-analysis. USA.gov. doi: 10.1136/bmjopen-2018-025808. Get the latest public health information from CDC: https://www.coronavirus.gov. doi: … A total of 147 gonorrhoea prevalence studies were identified from 56 countries. Their fragility limits their transmissibility to direct contact between mucous membranes or the direct exchange of infected secretions. A Bayesian approach to uncertainty analysis of sexually transmitted infection models. Neisseria gonorrhoeae is an obligate human pathogen and is the etiological agent of gonorrhea. 1999 Mar;3(1):39-52. doi: 10.1023/a:1021862113241. Author links open overlay panel Feng Wang a 1 Jing-Wei Liu c d 1 Yi-Zhun Li a Li-Jun Zhang b Jing Huang a Xiang-Sheng Chen c d Shao-Chun Chen c d Yue-Ping Yin c d. Show more. Ann Intern Med. 1995 Sep-Oct;6(5):345-7. doi: 10.1177/095646249500600507. However, the incidence is much lower in the European coun-tries, … doi: 10.1093/oxfordjournals.epirev.a036267. Neisseria gonorrhoeae; epidemiology (general); gonorrhoea; infertility.  |  Epub 2018 Feb 28. NIH COVID-19 is an emerging, rapidly evolving situation. The pooled mean prevalence of current gonorrhoea infection was estimated globally at 2.2% (95% CI 1.3% to 3.2%), with the highest prevalence in Africa at 5.0% (95% CI 1.9% to 9.3%). A. Pili 1. 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